The art style of Janco moved between the figurative and the abstract. In Israel he had many subjects: soldiers and battle situations, transit camps and immigrant types, Arabs, landscapes, and the Holocaust.
The wounded soldier virtually became the symbol of his work (Wounded Soldier, 1949, Israel Museum, Jerusalem). These soldiers had complex meanings. In some of the paintings they looked as if crucified, or praying, or like the figures of Picasso's Guernica.
Janco dealt with the theme of immigration from every possible angle. He described the crowded ships, the refugees stealing into the country sheltered by the darkness of night, particular immigrant groups like the Yemenites, tents and figures in the transit camps. In all of these paintings the expressive style seemed to be a reflection of his own experience.
Janco's arrival in Israel after many years on the world stage represented a significant contribution to Israeli art. Within weeks of his arrival, a group of gifted Israeli painters gathered around him, seeing an opportunity through him of effecting a desired change in Israel's artistic life. Janco's activism helped fulfill their expectations.